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BDBM50367668 CHEMBL1237331

SMILES: Fc1ccc(cc1)C1CC(N2CCN(CCn3c4ccccc4[nH]c3=O)CC2)c2cc(F)ccc12

InChI Key: InChIKey=DYLJDEUIZSKBJX-UHFFFAOYSA-N

Data: 3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50367668   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367668
PNG
(CHEMBL1237331)
Show SMILES Fc1ccc(cc1)C1CC(N2CCN(CCn3c4ccccc4[nH]c3=O)CC2)c2cc(F)ccc12
Show InChI InChI=1S/C28H28F2N4O/c29-20-7-5-19(6-8-20)23-18-27(24-17-21(30)9-10-22(23)24)33-14-11-32(12-15-33)13-16-34-26-4-2-1-3-25(26)31-28(34)35/h1-10,17,23,27H,11-16,18H2,(H,31,35)
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KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranes


J Med Chem 31: 2247-56 (1989)


Article DOI: 10.1021/jm00120a003
BindingDB Entry DOI: 10.7270/Q2JQ11K7
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50367668
PNG
(CHEMBL1237331)
Show SMILES Fc1ccc(cc1)C1CC(N2CCN(CCn3c4ccccc4[nH]c3=O)CC2)c2cc(F)ccc12
Show InChI InChI=1S/C28H28F2N4O/c29-20-7-5-19(6-8-20)23-18-27(24-17-21(30)9-10-22(23)24)33-14-11-32(12-15-33)13-16-34-26-4-2-1-3-25(26)31-28(34)35/h1-10,17,23,27H,11-16,18H2,(H,31,35)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.40n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranes


J Med Chem 31: 2247-56 (1989)


Article DOI: 10.1021/jm00120a003
BindingDB Entry DOI: 10.7270/Q2JQ11K7
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50367668
PNG
(CHEMBL1237331)
Show SMILES Fc1ccc(cc1)C1CC(N2CCN(CCn3c4ccccc4[nH]c3=O)CC2)c2cc(F)ccc12
Show InChI InChI=1S/C28H28F2N4O/c29-20-7-5-19(6-8-20)23-18-27(24-17-21(30)9-10-22(23)24)33-14-11-32(12-15-33)13-16-34-26-4-2-1-3-25(26)31-28(34)35/h1-10,17,23,27H,11-16,18H2,(H,31,35)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 160n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranes


J Med Chem 31: 2247-56 (1989)


Article DOI: 10.1021/jm00120a003
BindingDB Entry DOI: 10.7270/Q2JQ11K7
More data for this
Ligand-Target Pair