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BDBM50369380 CHEMBL606502

SMILES: [#7]-c1ncnc2n(cnc12)-[#6]-1-[#8]-[#6@H](\[#6]=[#6](\Br)Br)-[#6@@H](-[#8])-[#6@H]-1-[#8]

InChI Key: InChIKey=OMVJOQTWOUXKJW-DXNVRMHDSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369380   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosylhomocysteinase


(Homo sapiens (Human))
BDBM50369380
PNG
(CHEMBL606502)
Show SMILES Nc1ncnc2n(cnc12)C1O[C@H](C=C(Br)Br)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H11Br2N5O3/c12-5(13)1-4-7(19)8(20)11(21-4)18-3-17-6-9(14)15-2-16-10(6)18/h1-4,7-8,11,19-20H,(H2,14,15,16)/t4-,7-,8-,11?/m1/s1
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
3.10E+3n/an/an/an/an/an/an/an/a



Brigham Young University

Curated by ChEMBL


Assay Description
The kinetic constant for inhibition of S-adenosyl-homocysteine hydrolase by the compound


J Med Chem 41: 3078-83 (1998)


Article DOI: 10.1021/jm9801410
BindingDB Entry DOI: 10.7270/Q2MC90PC
More data for this
Ligand-Target Pair