BDBM50370935 CHEMBL1203937

SMILES CCOc1cc2ncnc(NCc3ccc(F)cc3)c2cc1OCC

InChI Key InChIKey=DEBQVAUIPWIBMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50370935   

TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)
Affinity DataIC50: >100nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)
Affinity DataIC50:  231nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed