BDBM50371698 CHEMBL408322::US9149492, 1

SMILES CCCCCCCC(=O)Nc1ccccc1-c1ccccc1

InChI Key InChIKey=CLTPDJWVYAJEKC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371698   

TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dartmouth College

US Patent
LigandPNGBDBM50371698(CHEMBL408322 | US9149492, 1)
Affinity DataIC50:  6.10E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
Universita Di Milano

Curated by ChEMBL
LigandPNGBDBM50371698(CHEMBL408322 | US9149492, 1)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of human ACAT2 expressed in insect Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dartmouth College

US Patent
LigandPNGBDBM50371698(CHEMBL408322 | US9149492, 1)
Affinity DataIC50:  6.09E+4nMAssay Description:Inhibition of human ACAT1 expressed in insect Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
Universita Di Milano

Curated by ChEMBL
LigandPNGBDBM50371698(CHEMBL408322 | US9149492, 1)
Affinity DataIC50:  2.30E+5nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In DepthDetails US Patent