BDBM50372141 CHEMBL256246

SMILES Nc1n[nH]c2cncc(-c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12

InChI Key InChIKey=MNZGLNJCEGVMQR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50372141   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372141(CHEMBL256246)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372141(CHEMBL256246)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372141(CHEMBL256246)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372141(CHEMBL256246)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372141(CHEMBL256246)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372141(CHEMBL256246)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article