BDBM50372148 CHEMBL403402

SMILES Nc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12

InChI Key InChIKey=DBXOMQJZSQLQED-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50372148   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372148(CHEMBL403402)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372148(CHEMBL403402)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372148(CHEMBL403402)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372148(CHEMBL403402)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372148(CHEMBL403402)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372148(CHEMBL403402)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article