BDBM50373172 C-6474572::CHEMBL265438
SMILES Oc1ccc(cc1)-c1nc2sc3CCCCc3c2c(=O)[nH]1
InChI Key InChIKey=OJQGZRUBLIAVFY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50373172
Affinity DataEC50: 2.60E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 5.77E+3nMAssay Description:Inhibition of GST-tagged BRD4 bromodomain (unknown origin) using biotinylated histone H4KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...More data for this Ligand-Target Pair