BDBM50373172 C-6474572::CHEMBL265438

SMILES Oc1ccc(cc1)-c1nc2sc3CCCCc3c2c(=O)[nH]1

InChI Key InChIKey=OJQGZRUBLIAVFY-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50373172   

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Lerner Research Institute

Curated by ChEMBL
LigandPNGBDBM50373172(C-6474572 | CHEMBL265438)
Affinity DataEC50:  2.60E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50373172(C-6474572 | CHEMBL265438)
Affinity DataIC50:  5.77E+3nMAssay Description:Inhibition of GST-tagged BRD4 bromodomain (unknown origin) using biotinylated histone H4KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50373172(C-6474572 | CHEMBL265438)
Affinity DataIC50:  7.32E+3nMAssay Description:Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed