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BDBM50374261 CHEMBL270431

SMILES: FC1CCN(Cc2nccn2-c2ccc(N3CCC(NS(=O)(=O)\C=C\c4ccc(Cl)s4)C3=O)c(F)c2)C1

InChI Key: InChIKey=RQKARFSPMLRNIR-KPKJPENVSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374261   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50374261
PNG
(CHEMBL270431)
Show SMILES FC1CCN(Cc2nccn2-c2ccc(N3CCC(NS(=O)(=O)\C=C\c4ccc(Cl)s4)C3=O)c(F)c2)C1
Show InChI InChI=1S/C24H24ClF2N5O3S2/c25-22-4-2-18(36-22)7-12-37(34,35)29-20-6-10-32(24(20)33)21-3-1-17(13-19(21)27)31-11-8-28-23(31)15-30-9-5-16(26)14-30/h1-4,7-8,11-13,16,20,29H,5-6,9-10,14-15H2/b12-7+
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MMDB

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PC cid
PC sid
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Similars

Article
PubMed
16.4n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of factor 10a


Bioorg Med Chem Lett 18: 28-33 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.019
BindingDB Entry DOI: 10.7270/Q29024PS
More data for this
Ligand-Target Pair