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BDBM50374269 CHEMBL271088

SMILES: CN(C)Cc1cn(cn1)-c1ccc(N2CCC(NS(=O)(=O)\C=C(/C)c3ccc(Cl)s3)C2=O)c(F)c1

InChI Key: InChIKey=ZJYXWKWXWRLPNP-FYWRMAATNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374269   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50374269
PNG
(CHEMBL271088)
Show SMILES CN(C)Cc1cn(cn1)-c1ccc(N2CCC(NS(=O)(=O)\C=C(/C)c3ccc(Cl)s3)C2=O)c(F)c1
Show InChI InChI=1/C23H25ClFN5O3S2/c1-15(21-6-7-22(24)34-21)13-35(32,33)27-19-8-9-30(23(19)31)20-5-4-17(10-18(20)25)29-12-16(26-14-29)11-28(2)3/h4-7,10,12-14,19,27H,8-9,11H2,1-3H3/b15-13+
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MMDB

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PC cid
PC sid
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Similars

Article
PubMed
29.3n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of factor 10a


Bioorg Med Chem Lett 18: 28-33 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.019
BindingDB Entry DOI: 10.7270/Q29024PS
More data for this
Ligand-Target Pair