BDBM50374401 CHEMBL407217

SMILES Oc1ccc(Cl)cc1NC(=O)Nc1cc(ccc1Cl)C(F)(F)F

InChI Key InChIKey=OUDXRNQPVSMGDW-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374401   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50374401(CHEMBL407217)
Affinity DataEC50:  3.40E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in Ach-induced current at -90 mV membra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50374401(CHEMBL407217)
Affinity DataEC50:  3.40E+3nMAssay Description:Activity at alpha7 nACh receptor assessed as modulation of acetylcholine-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)