BDBM50374614 CHEMBL254674

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n2c4ccccc4nc2n(-c2c(Cl)cc(Cl)cc2Cl)c3=O)cc1

InChI Key InChIKey=LSUOLDVCRALNRA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50374614   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50374614(CHEMBL254674)
Affinity DataIC50:  8nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50374614(CHEMBL254674)
Affinity DataIC50:  480nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50374614(CHEMBL254674)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p38-alpha by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50374614(CHEMBL254674)
Affinity DataIC50:  35nMAssay Description:Inhibition of Src by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed