BDBM50375731 CHEMBL271288
SMILES CCc1ccc(CN2CC[C@H](C2)NC(=O)CNC(=O)c2cc(ccc2N)C(F)(F)F)cc1
InChI Key InChIKey=SWSMNILBFGVKAL-GOSISDBHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50375731
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 0.890nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced calcium fluxMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Deltagen Research Laboratories (Former Combichem)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair