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BDBM50375915 CHEMBL436700

SMILES: CCOc1ccccc1N1CCN(CCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2)CC1

InChI Key: InChIKey=ZMQZCUIPVCGSQD-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50375915   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50375915
PNG
(CHEMBL436700)
Show SMILES CCOc1ccccc1N1CCN(CCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C30H33N5O3/c1-2-38-27-15-9-8-14-26(27)34-20-18-33(19-21-34)17-16-29(36)31-22-28-32-25-13-7-6-12-24(25)30(37)35(28)23-10-4-3-5-11-23/h3-15H,2,16-22H2,1H3,(H,31,36)
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 45.0n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50375915
PNG
(CHEMBL436700)
Show SMILES CCOc1ccccc1N1CCN(CCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C30H33N5O3/c1-2-38-27-15-9-8-14-26(27)34-20-18-33(19-21-34)17-16-29(36)31-22-28-32-25-13-7-6-12-24(25)30(37)35(28)23-10-4-3-5-11-23/h3-15H,2,16-22H2,1H3,(H,31,36)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 45n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair