BDBM50376012 CHEMBL270755

SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NCC3CC3)c2cc1OC

InChI Key InChIKey=LFDJFILTWUNEEP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50376012   

TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376012(CHEMBL270755)
Affinity DataIC50:  10nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376012(CHEMBL270755)
Affinity DataIC50:  11nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376012(CHEMBL270755)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376012(CHEMBL270755)
Affinity DataIC50:  11.0nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376012(CHEMBL270755)
Affinity DataIC50:  840nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376012(CHEMBL270755)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376012(CHEMBL270755)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed