BDBM50376120 CHEMBL259554

SMILES CCC(=O)c1c(-c2ccccc2)c2cc(Cl)ccc2c(=O)n1Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=ITAZALHTZBIKDO-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376120   

TargetMitogen-activated protein kinase 8(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376120(CHEMBL259554)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of JNK1 in rat H9c2 cells assessed as inhibition of anisomycin-induced cJun phosphorylation after 30 minsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376120(CHEMBL259554)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair