BDBM50376383 CHEMBL259972

SMILES COc1ccc(cc1)-c1noc(CC(O)=O)c1-c1ccc(OC)cc1

InChI Key InChIKey=DJEIHHYCDCTAAH-UHFFFAOYSA-N

Data  14 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50376383   

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universit£

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  440nMAssay Description:Inhibition of ovine COX-2 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Okayama University Graduate School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Okayama University Graduate School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  440nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universit£

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant ovine COX2 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin addition meas...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Okayama University Graduate School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Okayama University Graduate School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human COX2 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Okayama University Graduate School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Okayama University Graduate School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Okayama University Graduate School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  440nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  13nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Okayama University Graduate School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair