BDBM50376594 CHEMBL260120
SMILES C[C@@H](N(C)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)CC(N)=O
InChI Key InChIKey=GRHNSLXBGRDMSP-CZAAIQMYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50376594
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel
Curated by ChEMBL
Vrije Universiteit Brussel
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 1.06E+3nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse spinal cord assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00500nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse frontal cortex assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 7.97E+4nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+4nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 960nMAssay Description:Agonist activity at human DOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillat...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]naloxone from MOR in rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel
Curated by ChEMBL
Vrije Universiteit Brussel
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Displacement of [3H]deltorphin2 from DOR in rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Agonist activity at human MOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillat...More data for this Ligand-Target Pair