BDBM50377964 Cantil::Glycophenylate::MEPENZOLATE BROMIDE::Mepenzolate

SMILES C[N+]1(C)CCCC(C1)OC(=O)C(O)(c1ccccc1)c1ccccc1

InChI Key InChIKey=GKNPSSNBBWDAGH-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50377964   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Keio University

Curated by ChEMBL
LigandPNGBDBM50377964(Cantil | Glycophenylate | MEPENZOLATE BROMIDE | Me...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]NMS from human M2R expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Keio University

Curated by ChEMBL
LigandPNGBDBM50377964(Cantil | Glycophenylate | MEPENZOLATE BROMIDE | Me...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]NMS from human M2R expressed in CHOK1 cell membranes incubated for 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Keio University

Curated by ChEMBL
LigandPNGBDBM50377964(Cantil | Glycophenylate | MEPENZOLATE BROMIDE | Me...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]NMS from human M3R expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Keio University

Curated by ChEMBL
LigandPNGBDBM50377964(Cantil | Glycophenylate | MEPENZOLATE BROMIDE | Me...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]NMS from human M3R expressed in CHOK1 cell membranes incubated for 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50377964(Cantil | Glycophenylate | MEPENZOLATE BROMIDE | Me...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50377964(Cantil | Glycophenylate | MEPENZOLATE BROMIDE | Me...)
Affinity DataIC50:  6.49E+4nMAssay Description:Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed