BDBM50378235 CHEMBL461557

SMILES CC[C@H](CO)Nc1nc(NCc2ccc(cc2)-c2ccccc2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=BRJSFOFBYVFKCP-OAQYLSRUSA-N

Data  3 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378235   

LigandPNGBDBM50378235(CHEMBL461557)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant CDK2/cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Sus scrofa)
Universite Paris-Descartes

Curated by ChEMBL
LigandPNGBDBM50378235(CHEMBL461557)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig brain GSK3alpha/betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378235(CHEMBL461557)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at N-type Cav2.2 channel expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378235(CHEMBL461557)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed