BDBM50378305 CHEMBL583417

SMILES CC(C)n1cnc2c(NCc3ccc(s3)-c3nc(C)cs3)nc(N[C@H]3CC[C@H](N)CC3)nc12

InChI Key InChIKey=KTMGWYXHOHWEPU-WKILWMFISA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378305   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL

LigandBDBM50378305(CHEMBL583417)Copy SMILESCopy InChI

Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri

Curated by ChEMBL

LigandBDBM50378305(CHEMBL583417)Copy SMILESCopy InChI

Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI