BDBM50379241 CHEMBL2011479
SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1
InChI Key InChIKey=AADKPDGTJHDJAJ-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50379241
Affinity DataKi: 4.00E+4nMAssay Description:Non-competitive inhibition of human recombinant MAGL assessed as 7-hydroxycoumarin level using umbelliferyl arachidonate as substrate by luminescence...More data for this Ligand-Target Pair
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataIC50: 288nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataIC50: 676nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair