BDBM50379907 CHEMBL2011993
SMILES CN1C(N)=NC(CC2CC2)(C1=O)c1cccc(c1)-c1cccc(Cl)c1
InChI Key InChIKey=PKPHSCAXKJAHAV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50379907
Affinity DataKi: 350nMAssay Description:Inhibition of human BACE1 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP swedish and london mutant assessed as decrease of amyloid-beta40 level after 4 hrs by electrochemi...More data for this Ligand-Target Pair