BDBM50380392 CHEMBL2018445

SMILES COc1ccc(CN2CCc3c(C2)c2ccccc2n3Cc2ccc(cc2)C(=O)NO)cc1

InChI Key InChIKey=LWEJQWKYQBTESX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380392   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50380392(CHEMBL2018445)
Affinity DataIC50:  4.64E+3nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50380392(CHEMBL2018445)
Affinity DataIC50:  3.05nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed