BDBM50380618 CHEMBL2016868

SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2Cc3cccc(CNC(=O)Cc4ccc(CC(=O)NCc5cccc(C[C@@H](NS(=O)(=O)Cc6ccccc6)C(=O)N2)c5)cc4)c3)cc1

InChI Key InChIKey=UIBUHBYTPNMHCK-IOLBBIBUSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50380618   

TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  6.90nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  6.90nMAssay Description:Inhibition of plasmin by dixon plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  45.4nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  45.4nMAssay Description:Inhibition of thrombin by dixon plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  136nMAssay Description:Inhibition of plasma kallikrein by dixon plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  136nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  152nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  152nMAssay Description:Inhibition of factor 10a by dixon plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50380618(CHEMBL2016868)
Affinity DataKi:  564nMAssay Description:Inhibition of activated protein C by dixon plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed