BDBM50381097 CHEMBL2017557

SMILES CCC(O)(CC)c1ccc2cc([nH]c2c1)-c1n[nH]c2cc(sc12)-c1ccccc1

InChI Key InChIKey=YBKODNZGBUDZRA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50381097   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381097(CHEMBL2017557)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381097(CHEMBL2017557)
Affinity DataIC50:  441nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381097(CHEMBL2017557)
Affinity DataIC50:  203nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381097(CHEMBL2017557)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed