BDBM50381529 CHEMBL2017760

SMILES COCC(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(Cl)cc3)ccc2n1

InChI Key InChIKey=AYPYBHONFLZDMF-BJMVGYQFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50381529   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381529(CHEMBL2017760)
Affinity DataIC50:  45nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381529(CHEMBL2017760)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381529(CHEMBL2017760)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed