BDBM50381695 CHEMBL2023223

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccsc2)c1

InChI Key InChIKey=ALBFRPATCDNTBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50381695   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50381695(CHEMBL2023223)
Affinity DataIC50:  31nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50381695(CHEMBL2023223)
Affinity DataIC50:  9nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50381695(CHEMBL2023223)
Affinity DataIC50:  179nMAssay Description:Inhibition of Aurora B using 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed