BDBM50382011 CHEMBL2023298

SMILES CC1CCCN(Cc2cc(Nc3nc(C)cn4c(cnc34)-c3cnn(CC(=O)NCc4cccc(c4)C(F)(F)F)c3)sn2)C1

InChI Key InChIKey=ZFTVPSJPUDCIHD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50382011   

TargetAurora kinase B(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50382011(CHEMBL2023298)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50382011(CHEMBL2023298)
Affinity DataIC50:  413nMAssay Description:Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50382011(CHEMBL2023298)
Affinity DataIC50:  35nMAssay Description:Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed