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BDBM50382304 CHEMBL2024520

SMILES: NC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)CC1

InChI Key: InChIKey=PYTQKUTVNQGNKV-SHTZXODSSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382304   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50382304
PNG
(CHEMBL2024520)
Show SMILES NC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C19H28Cl2N4O/c20-17-6-5-16(13-18(17)21)25-11-9-24(10-12-25)8-7-14-1-3-15(4-2-14)23-19(22)26/h5-6,13-15H,1-4,7-12H2,(H3,22,23,26)/t14-,15-
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 29n/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat striatal membranes


Bioorg Med Chem Lett 22: 3437-40 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.104
BindingDB Entry DOI: 10.7270/Q2ZW1MZN
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50382304
PNG
(CHEMBL2024520)
Show SMILES NC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C19H28Cl2N4O/c20-17-6-5-16(13-18(17)21)25-11-9-24(10-12-25)8-7-14-1-3-15(4-2-14)23-19(22)26/h5-6,13-15H,1-4,7-12H2,(H3,22,23,26)/t14-,15-
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.320n/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 22: 3437-40 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.104
BindingDB Entry DOI: 10.7270/Q2ZW1MZN
More data for this
Ligand-Target Pair