BDBM50382374 CHEMBL2024530

SMILES CCc1ccccc1Sc1ccc2c(-c3c(Cl)cccc3Cl)c(=O)ncn2n1

InChI Key InChIKey=QDMADPOVSXTYKG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50382374   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382374(CHEMBL2024530)
Affinity DataIC50:  750nMAssay Description:Inhibition of p38alpha kinase using KRELVEPLTPSGEAPNQALLR as substrate for 20 mins by lactate dehydrogenase-coupled spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382374(CHEMBL2024530)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of p38alpha in human PBMC assessed as inhibition of LPS-induced TNFalpha production after 16 to 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382374(CHEMBL2024530)
Affinity DataIC50:  980nMAssay Description:Inhibition of p38alpha in human PBMC assessed as inhibition of LPS-induced IL1beta production after 16 to 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed