BDBM50382463 CHEMBL2023989

SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(C(O)=O)c(O)c1)C(=O)OC(C)(C)C

InChI Key InChIKey=PZIAIBCFVUIGPT-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50382463   

TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50382463(CHEMBL2023989)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of 5-carboxyfluorescein-labeled GpYLVLDKW from the STAT5b-SH2 domain after 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50382463(CHEMBL2023989)
Affinity DataKi:  7.90E+3nMAssay Description:Displacement of fluorescein-labeled phosphotyrosine-peptide derived from the interleukin-6 receptor subunit gp130 from the STAT3 after 15 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50382463(CHEMBL2023989)
Affinity DataKi: >2.50E+4nMAssay Description:Displacement of radioligand from the STAT1 after 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50382463(CHEMBL2023989)
Affinity DataIC50:  1.15E+5nMAssay Description:Binding affinity to Stat3 (unknown origin) using hSIE as probe preincubated for 30 mins followed by hSIE addition by electrophoretic mobility shift a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50382463(CHEMBL2023989)
Affinity DataIC50:  1.58E+4nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed