BDBM50382672 CHEMBL2024005
SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1CN(C[C@@H]1O)C(=O)P(O)(O)=O
InChI Key InChIKey=FVXOQJONSZSXSW-UHNVWZDZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50382672
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Competitive inhibition of PNP in human DoHH2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Competitive inhibition of human recombinant PNP using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human Jurkat cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human PBMC using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human K562 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human MINO cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Competitive inhibition of PNP in human MC116 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Competitive inhibition of PNP in human SU-DHL-1 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Competitive inhibition of PNP in human AML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Competitive inhibition of PNP in human CML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive inhibition of PNP in human OPM2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive inhibition of PNP in human HBL2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Competitive inhibition of PNP in human RPMI8226 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Competitive inhibition of PNP in human HBL2 tumor cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant PNP using MSEG as substrate preincubated with inhibitor within 10 to 20 mins measured after 5 mins by HPLC analysisMore data for this Ligand-Target Pair