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BDBM50383662 CHEMBL2029876

SMILES: CCOC(=O)C1Cc2ccccc2CN1C(=O)c1cccc2oc(C)cc12

InChI Key: InChIKey=JHRWKNIQAPFKKC-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383662   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor subfamily 1 group D member 1


(Homo sapiens)
BDBM50383662
PNG
(CHEMBL2029876)
Show SMILES CCOC(=O)C1Cc2ccccc2CN1C(=O)c1cccc2oc(C)cc12
Show InChI InChI=1S/C22H21NO4/c1-3-26-22(25)19-12-15-7-4-5-8-16(15)13-23(19)21(24)17-9-6-10-20-18(17)11-14(2)27-20/h4-11,19H,3,12-13H2,1-2H3
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>3.00E+3n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at Rev-erbalpha assessed as repression of transcription by luciferase-reporter gene assay


Bioorg Med Chem Lett 22: 3739-42 (2012)

More data for this
Ligand-Target Pair