BDBM50383853 CHEMBL2031147

SMILES CC(=O)N[C@@H](Cc1ccc(F)cc1)[C@H](O)CN[C@H]1C[C@@]2(C[C@H](O)C2)Oc2ncc(CC(C)(C)C)cc12

InChI Key InChIKey=WRMXZVCISFLWNB-CGDFKPNQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383853   

TargetBeta-secretase 1(Homo sapiens (Human))
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383853(CHEMBL2031147)
Affinity DataIC50:  14nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383853(CHEMBL2031147)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383853(CHEMBL2031147)
Affinity DataIC50:  41nMAssay Description:Inhibition of BACE1 in human HEK293 cells stably expressing APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed