BDBM50384482 CHEMBL2036207

SMILES CCCCC(=O)N(Cc1ccc2OCCOc2c1)c1cc(F)cc(c1)-c1nnn[nH]1

InChI Key InChIKey=IMXWHSQEAKBLFF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50384482   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384482(CHEMBL2036207)
Affinity DataKi:  2nMAssay Description:Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384482(CHEMBL2036207)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change incubated for 20 mins prior...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384482(CHEMBL2036207)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed