BDBM50384726 CHEMBL2037208

SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1

InChI Key InChIKey=HMMBZLXOFKQWRQ-UCQKPKSFSA-N

Data  25 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50384726   

TargetProto-oncogene tyrosine-protein kinase ROS(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  7nMAssay Description:Inhibition of TRKA by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of Tel-fused TIE1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Tel-fused SRC in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Tel-fused RET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  2nMAssay Description:Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Tel-fused LYN in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of Tel-fused MET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  21nMAssay Description:Inhibition of Tel-fused KIT in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Tel-fused JNK2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of Tel-fused INSR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of Tel-fused IGF1R in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  310nMAssay Description:Inhibition of Tel-fused FMS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of Tel-fused RON in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of Tel-fused FLT3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Tel-fused FLT1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tel-fused FGR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Tel-fused FGFR4 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of Tel-fused FGFR3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of Tel-fused EPHA3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of Tel-fused BMX in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of Tel-fused ALK in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  29nMAssay Description:Inhibition of TRKC by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of Tel-fused ZAP70 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed