BDBM50386749 CHEMBL2046883

SMILES Cc1ccc(NC(=O)Nc2nnc(Sc3ncnc4cc(OCCCN5CCOCC5)ccc34)s2)cc1

InChI Key InChIKey=LKXFSTAQMOENSC-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50386749   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human c-kitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human FLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human FLT4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human IGF-1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Pim1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human RetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human c-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed