BDBM50387288 CHEMBL2048853

SMILES CC(Sc1ccc(nn1)-c1ccccc1)C(=O)N(C1CC1)c1nc(C)cs1

InChI Key InChIKey=PUVLCLUXGUVHNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50387288   

TargetSolute carrier family 12 member 5(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50387288(CHEMBL2048853)
Affinity DataIC50:  570nMAssay Description:Antagonist activity at KCC2 expressed in human HEK293 cells assessed as decrease in Tl-stimulated fluorescence increase after 8 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 12 member 5(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50387288(CHEMBL2048853)
Affinity DataIC50:  152nMAssay Description:Antagonist activity at KCC2 expressed in human HEK293 cells assessed as decrease in Tl-stimulated fluorescence increase after 8 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 12 member 5(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50387288(CHEMBL2048853)
Affinity DataIC50:  570nMAssay Description:Antagonist activity at KCC2 expressed in human HEK293 cells assessed as decrease in Tl-stimulated fluorescence increase after 8 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed