BDBM50387569 CHEMBL2057714
SMILES C1CN2CCC1C21CCN(C1)c1cccnc1
InChI Key InChIKey=LIWBYJGLHCGRCM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50387569
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 560nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 7.60E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair