BDBM50387916 CHEMBL2058681

SMILES Oc1ccc(O)n1-c1cc(Cc2n[nH]c(=O)c3CCCNc23)ccc1F

InChI Key InChIKey=UEFYGOPDSKFOBV-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387916   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50387916(CHEMBL2058681)
Affinity DataKi:  1.40nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50387916(CHEMBL2058681)
Affinity DataEC50:  56nMAssay Description:Inhibition of PARP1 in H202-stimulated human C41 cells incubated for 30 mins prior to H2O2-treatment measured after 10 mins by FITC-based immunostain...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed