BDBM50388786 CHEMBL2062563

SMILES CC(=O)Nc1ccc2ccn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1

InChI Key InChIKey=DVDLZLUKYIFIOR-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50388786   

TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388786(CHEMBL2062563)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-terminal His6X-tagged recombinant human full length casein kinase-2alpha expressed in SF21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomeodomain-interacting protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388786(CHEMBL2062563)
Affinity DataIC50:  30nMAssay Description:Inhibition of HipK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388786(CHEMBL2062563)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388786(CHEMBL2062563)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388786(CHEMBL2062563)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388786(CHEMBL2062563)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length N-terminus His-tagged human CK2alpha expressed in insect Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as substrate after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388786(CHEMBL2062563)
Affinity DataIC50:  130nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388786(CHEMBL2062563)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of human ErgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed