BDBM50388882 CHEMBL2063115

SMILES Fc1cccc([C@@H]2CC[C@@H](OC(=O)N3CCC(CC3)n3c4cccnc4[nH]c3=O)c3ncccc3C2)c1F

InChI Key InChIKey=VUNYPRIWWJSQTR-UZUQRXQVSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50388882   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388882(CHEMBL2063115)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388882(CHEMBL2063115)
Affinity DataIC50:  0.220nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed