BDBM50389590 CHEMBL2069502
SMILES C1CC(CCO1)[C@H]1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
InChI Key InChIKey=WTEHMPUGVAOZBF-FYYLOGMGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50389590
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 369nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to mouse SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at mouse SST3 receptor expressed in CHO cells assessed as inhibition of forskolin/SS-14-stimulated cAMP accumulation preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [125I]SS-14 from mouse SST3 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human SST3 receptor expressed in CHO cells assessed as inhibition of forskolin/SS-14-stimulated cAMP accumulation preincubated...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Antagonist activity at human somatostatin receptor type 3 assessed as inhibition of cAMP levelsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Binding affinity to human somatostatin receptor type 3More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]SS-28 from human SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human SST4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to mouse SST1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to mouse SST2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to mouse SST4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]SS-14 from human SST3 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Displacement of [35S]MK499 from human Erg expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human SST1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human SST2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair