BDBM50389697 CHEMBL2070064::US10544104, Compound 46::US11247972, Compound 46::US9765037, Compound 46
SMILES CC(C)n1nc(-c2ccc3cc(OCc4ccccc4Cl)ccc3c2)c2c(N)ncnc12
InChI Key InChIKey=KLNHTCQQONFNPS-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50389697
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of human SRC using Ac-EIYGEFKKK-OH as substrate after 60 mins by phosphorimaging methodMore data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 10.6nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 102nMAssay Description:Two types of enzyme assays were developed to follow TgCDPK1 activity, a radiometric scintillation proximity assay measured the labeled γ-phospha...More data for this Ligand-Target Pair
TargetCalcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands(Cryptosporidium parvum (strain Iowa II))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 102nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 102nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetcGMP-dependent protein kinase()
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 10.6nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 10.6nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair