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BDBM50389749 CHEMBL2070070

SMILES: CCOc1ccc2cc(ccc2c1)-c1nn(C[C@@H](N)C(C)C)c2ncnc(N)c12

InChI Key: InChIKey=JJBVXBLSJXIUKY-GOSISDBHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50389749   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50389749
PNG
(CHEMBL2070070)
Show SMILES CCOc1ccc2cc(ccc2c1)-c1nn(C[C@@H](N)C(C)C)c2ncnc(N)c12
Show InChI InChI=1S/C22H26N6O/c1-4-29-17-8-7-14-9-16(6-5-15(14)10-17)20-19-21(24)25-12-26-22(19)28(27-20)11-18(23)13(2)3/h5-10,12-13,18H,4,11,23H2,1-3H3,(H2,24,25,26)/t18-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of human SRC using Ac-EIYGEFKKK-OH as substrate after 60 mins by phosphorimaging method


J Med Chem 55: 2416-26 (2012)


Article DOI: 10.1021/jm201713h
BindingDB Entry DOI: 10.7270/Q2P2706V
More data for this
Ligand-Target Pair