BDBM50390271 CHEMBL2070418

SMILES NC(=O)c1cccc(Oc2ccc(\C=C3/SC(=S)N(C3=O)c3ccc(OCCCN4CCCCC4)cc3)cc2)c1

InChI Key InChIKey=RCMNKVHGBTYZCC-RRAHZORUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390271   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Mus musculus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390271(CHEMBL2070418)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of IKKbeta in mouse CIA model spelonocytes assessed as inhibition of TNFalpha production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390271(CHEMBL2070418)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of IKKbeta using 5FAM-GRHDSGLDSMK-NH2 as substrate incubated for 10 mins prior to substrate addition by IMAP-TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed