BDBM50390412 CHEMBL2071339

SMILES NC(=O)[C@@H]1CCCN1C(=O)Nc1nc2ccc(cc2s1)-c1cnc(N)c(c1)C(F)(F)F

InChI Key InChIKey=BUYUSMTYAYHWLC-ZDUSSCGKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390412   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390412(CHEMBL2071339)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390412(CHEMBL2071339)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110gamma by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390412(CHEMBL2071339)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110beta by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390412(CHEMBL2071339)
Affinity DataIC50:  540nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110delta by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed