BDBM50391300 CHEMBL162691

SMILES OC(=O)CC\C=C/CO[C@H]1[C@@H](CC[C@@H]1N1CCCCCC1)OCc1ccc(cc1)-c1ccncc1

InChI Key InChIKey=HCLFUHWPLXVRIS-HLOJMEPRSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391300   

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391300(CHEMBL162691)
Affinity DataIC50:  631nMAssay Description:In vitro TXA2 synthase antagonism through inhibition of collagen induced thromboxane-A2 production in human citrated whole bloodChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391300(CHEMBL162691)
Affinity DataKd:  10nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole blood.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50391300(CHEMBL162691)
Affinity DataKd:  79.4nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article