BDBM50391809 CHEMBL2146887

SMILES OC1CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=COACPTNNJAFVAN-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391809   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50391809(CHEMBL2146887)Copy SMILESCopy InChI

Affinity DataIC50:  44nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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