BDBM50391861 CHEMBL2147284

SMILES CCc1ccc(cc1)-c1ccccc1C(=O)Nc1ccc2cc(ccc2n1)C(=O)N[C@H](C(=O)N(C)Cc1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=OLCIBVKTMMFOTI-LHEWISCISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391861   

TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50391861(CHEMBL2147284)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed